¶ – W&M undergraduate
§ – W&M masters student
¤ – High School Students
# – W&M faculty/staff colleague
@– indicates shared first authorship and equal contributions.
38. Zimmerman, EH¶, EL Ramsey¶, KE Hunter¶, SM Villadelgado¶, CM Phillips¶, RT Shipman¶, MH. Forsyth. The Helicobacter pylori Methylome is Acid-Responsive due to Regulation by the Two-Component System ArsRS and the Type I DNA Methyltransferase HsdM1 (HP0463). 2024. J. Bacteriol. January. https://journals.asm.org/doi/epub/10.1128/jb.00309-23 .
37. Allen, MG§, Bate, MY¶, Tramonte, LM¶, Avalos, EY¶, Loh, JT Cover, TL, & MH Forsyth. Regulation of Helicobacter pylori urease and acetone carboxylase genes by nitric oxide and the CrdRS two-component system. 2023. Microbiol Spectrum 2023 Jan 10:e0463322. doi: 10.1128/spectrum.04633-22. PMID: 36625670
36. Loh, JT, M Shum, SDR. Jossart, A Campbell, WH McDonald, M. Scholz, MS McClain, MH Forsyth, & TL Cover. Delineation of the pH-responsive regulon controlled by the Helicobacter pylori ArsRS two- component system. Infect. & Immun. 2021. March 17: 89(4):e00597-20. doi: 10.1128/IAI.00597-20. https://pubmed.ncbi.nlm.nih.gov/33526561/
35. Anders KR, Barekzi N, Best AA, Frederick GD, Mavrodi DV, Vazquez E; SEA- PHAGES, Amoh NYA¶, Baliraine FN, Buchser WJ#, Cast TP, Chamberlain CE, Chung HM, D’Angelo WA, Farris CT, Fernandez-Martinez M, Fischman HD, Forsyth MH, Fortier AG, Gallo KF, Held GJ, Lomas MA, Maldonado-Vazquez NY, Moonsammy CH, Namboote P, Paudel S, Polley SM, Reyes GM, Rubin MR, Saha MS#, Stukey J, Tobias TD, Garlena RA, Stoner TH, Cresawn SG, Jacobs-Sera D, Pope WH, Russell DA, Hatfull GF. Genome Sequences of Mycobacteriophages Amgine, Amohnition, Bell96, Cain, DarthP, Hammy, Krueger, Last Hope, Peanam, PhelpsODU, Phrank, SirPhilip, SLmphazie, and Unicorn. Genome Announc. 2017 Dec.7;5(49). pii: e01202-17. doi: 10.1128/genomeA.01202-17. PMID: 29217790. https://pubmed.ncbi.nlm.nih.gov/29217790/
34. Bonilla JA, Isern S, Findley AM, Klyczek KK, Michael SF, Saha M.S. #, Buchser W.J. #, Forsyth MH, Paudel S.§, Gissendanner CR, Wiedemeier AMD, Alonzo FL; University of Wisconsin–River Falls SEA-PHAGES; Florida Gulf Coast University SEA-PHAGES; University of Louisiana–Monroe SEA-PHAGES; William & Mary SEA-PHAGES, Garlena RA, Russell DA, Pope WH, Cresawn SG, Jacobs-Sera D, Hatfull GF. 2017. Genome Sequences of 19 Rhodococcus erythroplolis Cluster CA Phages. Genome Announc. 2017 Dec 7;5(49). pii: e01201-17. doi: 10.1128/genomeA.01201-17. PMID: 29217789. https://pubmed.ncbi.nlm.nih.gov/29217789/
33. Bullock, K., Shaffer, C., Ousman S., Forsyth MH, McClain M., and T.L. Cover. 2017. Genetic signatures for Helicobacter pylori strains of West African origin. PLoS ONE. Nov 29;12(11):e0188804. doi: 10.1371/journal.pone.0188804. eCollection 2017. https://pubmed.ncbi.nlm.nih.gov/29186206/
32. Horridge, D.N. ¶, Begley, A.A. ¤, Kim, J. ¶, Aravindan, N. ¶, Fan, K¶. and M.H. Forsyth. 2017. Outer Inflammatory Protein A (OipA) of Helicobacter pylori is Regulated by Host Cell Contact and Mediates CagA Translocation and Interleukin-8 Response Only in the Presence of a Functional cag Pathogenicity Island Type IV Secretion System. Pathogens and Disease. (75)8:30 Nov. 2017. https://pubmed.ncbi.nlm.nih.gov/29040466/
31. Acio-Pizzarello C.R.¶, Acio, A.A.¶, Choi E.J.¶,¤, Bond K.¶, Kim J¶, Kenan A.C.¶, Chen J.¶ & M.H. Forsyth. 2017. Determinants of the Regulation of Helicobacter pylori Adhesins Include Repeat Sequences in Both Promoter and Coding regions as well as the Two Component System, ArsRS. J. Med. Microbiol. 66:798-807. https://pubmed.ncbi.nlm.nih.gov/28598306/
30. Krishna U, Romero-Gallo J, Suarez G, Azah A, Krezel AM, Varga MG, Forsyth MH, Peek RM Jr. 2016. Genetic Evolution of a Helicobacter pylori Acid Sensing Histidine Kinase and Gastric Disease. J. Infect. Dis. 214:644-648. https://pubmed.ncbi.nlm.nih.gov/27190191/
29. Carpenter BM, West AL, Gancz H., Servetas SL, Pich OQ, Gilbreath JJ, Hallinger DR§, Forsyth MH, Merrell DS, Michel SL. 2015. Crosstalk between the HpArsRS two-component system and HpNikR is necessary for maximal activation of urease transcription. Front. Microbiol. 6:558. https://pubmed.ncbi.nlm.nih.gov/26124751/
28. Harvey V.C.¶@, Acio C.R.¶@, Bredehoft A K.¶, Zhu L.1¶, Hallinger D. R.§, Quinlivan-Repasi V.2§, Harvey SE.¶, & M. H. Forsyth. 2014. Repetitive sequence variations in the promoter region of the adhesin encoding gene sabA of Helicobacter pylori affect transcription. J. Bacteriol. 196:3421-3429. https://pubmed.ncbi.nlm.nih.gov/25022855/
27. Hallinger D.R. §, J. Romero-Gallo, R.M. Peek Jr., & M. H. Forsyth. 2012. Polymorphisms of the acid sensing histidine kinase gene arsS in Helicobacter pylori populations from anatomically distinct gastric sites. Microbial Pathogenesis. 53:227-233. https://pubmed.ncbi.nlm.nih.gov/22940419/
26. Pope WH, Ferreira CM, Jacobs-Sera D, Benjamin RC, Davis AJ, Dejong RJ, Elgin SC, Guilfoile FR, Forsyth MH, Harris AD, Harvey SE¶1, Hughes LE, Hynes PM, Jackson AS¶1, Jalal MD, MacMurray E.A.§, Manley CM, McDonough MJ1¶, Mosier JL, Osterbann LJ, Rabinowitz HS, Rhyan CN, Russell DA, Saha M.S. #, Shaffer CD, Simon SE, Sims EF, Tovar IG, Weisser EG, Wertz JT, Weston-Hafer KA, Williamson KE, Zhang B, Cresawn SG, Jain P, Piuri M, Jacobs WR Jr, Hendrix RW, Hatfull GF. 2011. Cluster K Mycobacteriophages: Insights into the Evolutionary Origins of Mycobacteriophage TM4. PLoS One. 2011;6(10):e26750. Epub 2011 Oct 28. https://pubmed.ncbi.nlm.nih.gov/21298013/
25. Pope, W., (Authors)~180 Perz, A¶ Whelan, H. ¶, Walton, J. ¶, Jackson, A. ¶, Harvey, S¶, McDonough M¶., Forsyth, MH, Saha, M. #, Williamson K. #et al. 2011. Expanding the diversity of mycobacteriophages: Insights into genome architecture and evolution. PLoS One. 2011 Jan 27;6(1):e16329. PMID: 21298013. https://pubmed.ncbi.nlm.nih.gov/22053209/
24. Gunderson A.R.§, Forsyth M.H., and J.P. Swaddle#. 2009. Evidence that plumage bacteria influence feather coloration and body condition of a passerine. Journal of Avian Biology 40:440-447.
23. Goodwin A.C.¶@, Weinberger D. M.¶@, Ford C.B.§, Nelson J.E.¶, Snider J.D. ¶, Hall J.D. ¶, Paules C.I. ¶, Peek R.M. Jr., and MH Forsyth. 2008. Expression of the Helicobacter pylori adhesin SabA is controlled via phase variation and the ArsRS signal transduction system. Microbiology. 154:2231-2240. https://pubmed.ncbi.nlm.nih.gov/18667556/
22. Gunderson A.§, Frame A.¶, Swaddle J.P.#, and M.H. Forsyth. 2008. Role of Melanin in bacterial degradation of avian Feathers: Is it Really So Black and White. J. Avian Biol. 39:539-545.
21. Terry C.E.¶, McGinnis L.M.¶, Madigan K.C.¶ Cao P., Cover T. L., Liechti G.W. §, Peek R. M. Jr., and M.H. Forsyth. 2005. Genomic Comparison of cag Pathogenicity Island (PAI)-Positive and –Negative Helicobacter pylori Strains: Identification of Novel Markers for cag PAI-Positive Strains. Infect. Immun. 73:3794-3798. https://pubmed.ncbi.nlm.nih.gov/15908415/
20. Whitaker J. M. §, Cristol D.A. #, and M. H. Forsyth. 2005. Prevalence and Genetic Diversity of Bacillus licheniformis in Avian Plumage. J. Field Ornithol. 76:265-271.
19. Cristol D.A.#, Armstrong J. L.¶, Whitaker J. M.§, and M. H. Forsyth. 2005. Feather Degrading Bacteria Do Not Affect Feathers on Captive Northern Cardinals. Auk. 122:222-230.
18. Shannon L. McNulty¶@, Beth M. Mole¶@, D. Dailidiene, I. Segal, O. Secka, R. A. Adegbola, J. E. Thomas, Erik M. Lenarcic¶, R. M. Peek, Jr., D. E. Berg, M. H. Forsyth. 2004. Novel 180bp and 480 bp Insertion/Deletions Associated with African and African-American Strains of Helicobacter pylori. J. Clin. Microbiol. 42:5658-5663. https://pubmed.ncbi.nlm.nih.gov/15583296/
17. Loh J. T., Forsyth M. H., and T. L. Cover. 2004. Growth Phase Regulation of flaA Expression in Helicobacter pylori is luxS Dependent. Infect. Immun. 72:5506-5510. https://pubmed.ncbi.nlm.nih.gov/15322055/
16. McGowan C. C., Necheva A., Blaser M. J., Forsyth M. H., and T. L. Cover. Promoter Structure of Helicobacter pylori genes Transcribed under Low pH Conditions. Mol. Microbiol. 48:1225-1239. https://pubmed.ncbi.nlm.nih.gov/12787351/
15. Forsyth M. H., Cao, P., Garcia, P. P. #, Hall, J. D. ¶, and T. L. Cover. 2002. Genome-Wide Transcriptional Profiling in a Histidine Kinase Mutant of Helicobacter pylori Identifies Members of a Regulon. J. Bacteriol. 184:4630-4635. https://pubmed.ncbi.nlm.nih.gov/12142435/
14. Forsyth M.H., and T. L. Cover. 2000. Intercellular communication in Helicobacter pylori : luxS is essential for the production of an extracellular signaling molecule. Infect. Immun. 68:3193-3199. https://pubmed.ncbi.nlm.nih.gov/10816463/
13. Peek, Jr., R. M., M. J. Blaser, D. J. Mays, M. H. Forsyth, T. L. Cover, S. Y. Song, U. Krishna, and J. A. Pietenpol. 1999. Helicobacter pylori strain-specific genotypes in modulation of the gastric epithelial cell cycle. Cancer Res. 59:6124-6131. https://pubmed.ncbi.nlm.nih.gov/10626802/
12. Forsyth M. H., and T. L. Cover. 1999. Mutational analysis of the vacA promoter provides insight into gene transcription in Helicobacter pylori. J. Bacteriol. 181:2261-2266. https://pubmed.ncbi.nlm.nih.gov/10094707/
11. Goh, M. S., T. S. Gorton, M.H. Forsyth,K. E.Troy, and S. J. Geary. 1998. Molecular and biochemical analysis of a 105 kDa Mycoplasma gallisepticum cytadhesin (GapA). Microbiology 144:2971-2978. https://pubmed.ncbi.nlm.nih.gov/9846732/
10. Forsyth M. H., J.C. Atherton, M.J. Blaser, and T. L. Cover. 1998. Heterogeneity in levels of vacuolating cytotoxin gene (vacA ) transcription among Helicobacter pylori strains. Infect. Immun. 66:3088-3094. https://pubmed.ncbi.nlm.nih.gov/9632570/
9. Cao, P., M. S. McClain, M.H. Forsyth,and T. L. Cover 1998. Extracellular release of antigenic proteins by Helicobacter pylori. Infect. Immun. 66:2984-2986. https://pubmed.ncbi.nlm.nih.gov/9596777/
8. Karita, M., M. Etterbeek, M.H. Forsyth,M. K. R.Tummuru, and M.J. Blaser. 1997. Characterization of the Helicobacter pylori dapE gene; a conditionally lethal dapE – mutant and the implications for treatment and a vaccine. Infect. Immun. 65:4158-4164. https://pubmed.ncbi.nlm.nih.gov/9317022/
7. Frasca, S., L. Hinckly, M.H. Forsyth,T. S.Gorton, S. J. Geary, and H.J. Van Kruiningen. 1997. Conjunctivitis and episcleritis in a European Starling (Sturnus vulgaris ) associated with a novel mycoplasma, Mycoplasma sturni. J. Wildlife Dis. 33:336-339. https://pubmed.ncbi.nlm.nih.gov/9131571/
6. Forsyth, M.H., J. G. Tully, S. Frasca, L. Hinckley, T. S. Gorton, H. J. Van Kruiningen, and S.J. Geary. 1996. Mycoplasma sturni sp. nov., from the conjuntiva of a European Starling (Sturnus vulgaris). Int. J. Systematic Bacteriol. 46:716-719. https://pubmed.ncbi.nlm.nih.gov/8782681/
5. Forsyth, M.H., and S.J. Geary. 1996. The repetitive element, Rep MP 1, of Mycoplasma pneumoniae exists as a core element within a larger repetitive mosaic. J. Bacteriol. 178: 917-921. https://pubmed.ncbi.nlm.nih.gov/8550534/
4. Forsyth, M.H., S. Saoud, and S.J. Geary. 1995. Cloning and transcriptional analysis of the genes for the class II topoisomerase, DNA gyrase, of Mycoplasma gallisepticum. Gene 163:161-162. https://pubmed.ncbi.nlm.nih.gov/7557470/
3. Geary, S.J., M.H. Forsyth,S.Saoud, D. E. Berg, G. Wang, and C.M. Berg. 1994. Random amplified polymorphic DNA fingerprinting of Mycoplasma gallisepticum. Mol. Cell. Probes. 8:311-316. https://pubmed.ncbi.nlm.nih.gov/7870072/
2. Geary, S.J., J. A. Ryan, M.H. Forsyth,and G.V. Sasseville. 1993. Development of monoclonal antibodies for the detection of mycoplasma infection and contamination. Mol.and Cell. Probes 7:133-138. https://pubmed.ncbi.nlm.nih.gov/8321252/
1. Forsyth, M.H., M. E. Tourtellotte, and S.J. Geary. 1992. Localization of an immunodominant 64 kDa lipoprotein (LP 64) in the membrane of Mycoplasma gallisepticum and its role in cytadherence. Mol. Microbiol. 6:2099-2106. https://pubmed.ncbi.nlm.nih.gov/1406251/
Book Chapter:
Geary, S.J., and M.H. Forsyth. 1996. PCR: random amplified polymorphic DNA fingerprinting. in Molecular and Diagnostic Procedures in Mycoplasmology Vol. 2, Chapter A8. 81-85. J.G. Tully and S. Razin eds. Academic Press, New York.